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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“RationaleGrowing evidence indicates that the main psychoactive ingredient in the illegal drug “ecstasy” methylendioxymethamphetamine ) causes reduced activity in the serotonin and gamma-aminobutyric acid (GABA) systems in humans.”
Alterations to global but not local motion processing in long-term ecstasy (MDMA) users“It is indicated that MDMA alters the expression of several proteins involved in GABA neurotransmission, thus having critical effect on thermoregulation and MDMA acute toxicity.”
“Repeated exposure to MDMA diminished the number of parvalbumin-positive GABA interneurons in the dentate gyrus of the hippocampus, an effect that was attenuated by ketoprofen treatment.”
MDMA Increases Glutamate Release and Reduces Parvalbumin-Positive GABAergic Cells in the Dorsal Hippocampus of the Rat: Role of Cyclooxygenase“ MDMA may control these genes in a combined fashion, assigning GABA a pivotal role in MDMA activities.”
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