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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Gamma-Aminobutyric Acid and Muscarinic Agonists

Research Papers that Mention the Interaction

Previous in vitro studies have shown that muscarinic agonists increase GABA release and reduce the glutamatergic synaptic input to lamina II interneurons through GABAB receptors in the spinal cord.
Neuroscience  •  2004  |  View Paper
Muscarinic agonists (oxotremorine, arecoline) induce a rapid decrease of GABA level and an increase of its destruction, indicative of an increased activity of GABA synapses in basal ganglia and brain stem.
Annali dell'Istituto superiore di sanita  •  1978  |  View Paper