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Last Updated: 3 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Muscarinic Agonists

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supplement:

Gamma-Aminobutyric Acid

drug:

Muscarinic Agonists

Research Papers that Mention the Interaction

“Previous in vitro studies have shown that muscarinic agonists increase GABA release and reduce the glutamatergic synaptic input to lamina II interneurons through GABAB receptors in the spinal cord.”

Activation of muscarinic receptors inhibits spinal dorsal horn projection neurons: role of GABAB receptors

Neuroscience • 2004 | View Paper

“ Muscarinic agonists (oxotremorine, arecoline) induce a rapid decrease of GABA level and an increase of its destruction, indicative of an increased activity of GABA synapses in basal ganglia and brain stem.”

Regulation of gamma-aminobutyric acid metabolism in different brain structures by cholinergic and adrenergic drugs.

Annali dell'Istituto superiore di sanita • 1978 | View Paper

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