Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: a month ago

Possible Interaction: Gamma-Aminobutyric Acid and Methohexital

Research Papers that Mention the Interaction

Perfusion of slices with 10 to 100 microM MTH caused no significant change in glutamatergic transmission in the hippocampal CA1 region, but enhanced gamma-aminobutyric acid (GABA)A-mediated inhibitory postsynaptic currents and induced spontaneous inhibitory postsynaptic currents in neocortical and hippocampal CA1 neurons.
The Journal of pharmacology and experimental therapeutics  •  1998  |  View Paper
2 A high, supra-anaesthetic concentration of methohexitone increased the uptake of both D-aspartate and GABA.
British journal of pharmacology  •  1982  |  View Paper
4 Thiopentone, pentobarbitone, methohexitone and hydroxydione inhibited K+-stimulated GABA and D-aspartate release.
British journal of pharmacology  •  1981  |  View Paper