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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Gamma-Aminobutyric Acid and Meprobamate

Research Papers that Mention the Interaction

In "extrasynaptic" (α1β3δ and α4β3δ) receptors, meprobamate enhanced EC20 and saturating GABA currents, and directly activated these receptors.
Meprobamate modulates GABAA ( γ-aminobutyric acid Type A) receptors , and has barbiturate-like activity.
European journal of pharmacology  •  2016  |  View Paper
GABA enhanced the displacing potencies of depressants of most diverse chemical structures: diaryltriazine (LY 81067), pyrazolopyridine (etazolate), cinnamide, glutarimide, 2,3-benzodiazepine (tofizopam) and alcohol derivatives, barbiturates, (+)etomidate, methaqualone and meprobamate.
Life sciences  •  1988  |  View Paper