supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Isoproterenol
Research Papers that Mention the Interaction
“Intracerebroventricular administration of isoproterenol increased GABA content in PVN dialysates.”
GABAB receptors in the hypothalamic paraventricular nucleus mediate &bgr;‐adrenoceptor‐induced elevations of plasma noradrenaline in rats“Here we show that NA and isoproterenol (ISO), a beta‐adrenergic agonist, increased [3H]‐GABA uptake in mice FC, while alpha1‐adrenergic agonist phenylephrine had no effect.”
“Previous in vivo studies have shown that microiontophoretic application of norepinephrine (NE) and isoproterenol (ISO) can enhance gamma-aminobutyric acid (GABA)-induced depressant responses of rat somatosensory cortical neurons.”
“Furthermore, in aged F344 rats, local applications of ISO frequently attenuated (negatively modulated) GABA responses of cerebellar Purkinje neurons and ethanol decreased further these attenuated GABA responses.”
“In this study, we confirmed that microiontophoretically applied norepinephrine (NE) and isoproterenol potentiate the depressant effects of locally-applied gamma-aminobutyric acid (GABA) on cerebellar Purkinje neurons of anesthetized rats.”
“3 Noradrenaline, but not isoprenaline inhibited the evoked release of [3H]‐GABA.”
“Dopamine (DA), noradrenaline (NA), isoprenaline , clonidine and dibutyryl cyclic AMP decreased the GABA release from the striatum.”
“ Isoproterenol increased the GABA content of the SCG but did not change the pineal gland GABA levels.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback