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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Imipenem
Research Papers that Mention the Interaction
“Although the exact mechanism for seizure induction cannot be determined from these cases, potential drug interactions exist, because theophylline, imipenem , and ciprofloxacin are all believed to increase excitation of the central nervous system by inhibition of γ-aminobutyric acid binding to receptors.”
Seizures in Patients Simultaneously Receiving Theophylline and Imipenem or Ciprofloxacin or Metronidazole“In addition, Imi acts on the central nervous system by inhibition of GABA neurotransmission and Msc, a selective GABAA agonist, was able to protect against seizures induced by Imi.”
Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice
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