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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Guanidines

supplement:

Guanidines

Research Papers that Mention the Interaction

SummaryGamma-aminobutyric acid depressed the potassium contraction of the skeletal muscles and its sensitization to potassium ions caused by guanidine , aminopyridine, veratrine, and had no material effect on the aceytlcholine muscle contractions.
Bulletin of Experimental Biology and Medicine  •  2004  |  View Paper
Guanidine , methylguanidine, creatinine, and guanidinosuccinic acid reversibly and in a dose‐dependent manner inhibited both GABA and glycine responses.
The inhibitory effect of guanidine and methylguanidine on responses to GABA was additive.
The results suggest that guanidine , methylguanidine, creatinine, and guanidinosuccinic acid inhibited responses to the inhibitory neurotransmitters GABA and glycine by blocking the chloride channel.
Annals of neurology  •  1990  |  View Paper