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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Glyburide
Research Papers that Mention the Interaction
“Diazoxide caused a twofold greater decrease in GABA levels, and glybenclamide increased VMH GABA levels by 57%.”
ATP-Sensitive K+ Channels Regulate the Release of GABA in the Ventromedial Hypothalamus During Hypoglycemia“Co-administration of an insulin secretagogue such as glibenclamide (Glib) along with GABA may enhance the pancreatic insulin output in T1D.”
“ GABA and Glib (5 mg/kg) combination therapy achieved far better control over hyperglycaemia and related pathogenic conditions (b.w.,”
“ GABA and Glib synergistically augmented insulin secretion that can be used to manage T1D and its complications.”
“ GABA has the potential to remarkably enhance the therapeutic outcome in diabetic patients and reduce the dose of existing anti-diabetic drugs such as Glib.”
Evaluation of Gamma Amino Butyric Acid (GABA) and Glibenclamide Combination Therapy in Streptozotocin Induced Diabetes.
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