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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Ghrelin
Research Papers that Mention the Interaction
“Furthermore, in primary cortical neurons, ghrelin reduces GABA release through a CPT1A reduction.”
Ghrelin Causes a Decline in GABA Release by Reducing Fatty Acid Oxidation in Cortex“Nanomolar concentrations of GABA markedly inhibited ghrelin-activation of isolated NPY-GFP neurons, consistent with chronic suppression of ghrelin action in vivo.”
“It has recently been shown that ghrelin neurons increase the activities of GABA and NPY in the brain.”
“Therefore, it is possible to speculate that ghrelin acts in the hippocampus to modulate seizures via GABA.”
GABAB Receptor Blockade Prevents Antiepileptic Action of Ghrelin in the Rat Hippocampus.
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