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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Galantamine
Research Papers that Mention the Interaction
“In rat hippocampal and human cerebral cortical slices, 1 microM galantamine , acting as a nicotinic APL, increased gamma-aminobutyric acid (GABA) release triggered by 10 microM acetylcholine (ACh).”
The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system.“Additionally, Parkinsonian motor features and focal neurological signs are seen often in patients suffering from VaD. Recent developments in understanding the pathophysiology of the … with coexisting CVD and those with VaD. Galantamine has demonstrated long-term efficacy in the treatment of VaD. In addition to inhibiting acetylcholinesterase, galantamine … GABA), …).”
“Therefore, nefiracetam and galantamine are hypothesized to cause stimulations of the glutamate and GABA systems via stimulation of nAChRs.”
Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons
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