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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“It follows that if both decreasing excitatory activity with glutamatergic antagonists and increasing inhibitory activity with GABA agonists can reduce nicotineinduced increases in DA, a drug which possesses both mechanisms might also suppress nicotine-induced increases in neurotransmitter activity.”
Topiramate selectively attenuates nicotine‐induced increases in monoamine release“The glutamatergic agonists NMDA, kainate, and AMPA also induced a significant [3H]GABA release.”
“Depolarizing glutamate receptor agonists (glutamate, aspartate and kainic acid) applied in an in vitro perfusion system, stimulated massive release of [3H]GABA from frog and chick retina but not from rat retina.”
“Combinations of neuroprotective agents such as glutamate antagonists and calcium channel antagonists may be additive, and other combinations of neuroprotective agents, such as a glutamate antagonist with a gamma-aminobutyric acid (GABA) agonist, have even shown synergism in a rat stroke model.”
Combination treatment for acute ischemic stroke: A ray of Hope?
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