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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Dihydrotestosterone

Research Papers that Mention the Interaction

TTX reduced PSC size below control values, indicating DHT may augment presynaptic GABA release but inhibits the postsynaptic GnRH neuron response.
Biology of reproduction  •  2005  |  View Paper
Pulse-chase experiments showed that GABA inhibited in a dose-dependent manner the conversion of tritiated pregnenolone into radioactive steroids, including 17-hydroxy-pregnenolone, progesterone, 17-hydroxy-progesterone, dehydroepiandrosterone, and dihydrotestosterone.
Proceedings of the National Academy of Sciences of the United States of America  •  2000  |  View Paper
4) Dihydrotestosterone had no effect on amygdaloid or septal concentrations but was effective in reducing GABA concentration in the midbrain. (
Brain Research  •  1978  |  View Paper