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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Cyclothiazide
Research Papers that Mention the Interaction
“In addition, the prominent membrane current rebound when co‐application of GABA and CTZ was terminated suggests that the binding site for CTZ on the GABAC receptor is distinct from that for GABA, and that CTZ acts as a non‐competitive antagonist on the GABAC receptor.”
Cyclothiazide: a subunit‐specific inhibitor of GABAC receptors“We found that CTZ reversibly inhibited both evoked and spontaneous inhibitory postsynaptic currents, as well as GABA application-induced membrane currents, in a dose-dependent manner.”
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