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Discover Supplement-Drug Interactions

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Last Updated: a month ago

Possible Interaction: Gamma-Aminobutyric Acid and Cyclothiazide

Research Papers that Mention the Interaction

In addition, the prominent membrane current rebound when co‐application of GABA and CTZ was terminated suggests that the binding site for CTZ on the GABAC receptor is distinct from that for GABA, and that CTZ acts as a non‐competitive antagonist on the GABAC receptor.
The Journal of physiology  •  2008  |  View Paper
We found that CTZ reversibly inhibited both evoked and spontaneous inhibitory postsynaptic currents, as well as GABA application-induced membrane currents, in a dose-dependent manner.
Proceedings of the National Academy of Sciences of the United States of America  •  2003  |  View Paper