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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Calcium Supplement

Research Papers that Mention the Interaction

Application of the neurotransmitters GABA , glutamate and acetylcholine induced depolarizing calcium signal changes in neuronal cells providing evidence for the excitatory effects of these ligand-gated ion channels during maturation in vitro.
Stem Cell Research & Therapy  •  2013  |  View Paper
The transient increase in intracellular calcium following the depolarizing action of GABA leads to inhibition of DNA synthesis and cell proliferation.
Front. Neural Circuits  •  2013  |  View Paper
Through the depolarization of immature cerebellar neurons, GABA increases intracellular calcium and the phosphorylation of mitogen-activated protein kinase (MAPK) and Calmodulin-Dependent Protein Kinase II CaMKII.
International review of neurobiology  •  2005  |  View Paper
These results indicate that GABA may be involved in the modulation of the AR and the fertilization process in capacitated human spermatozoa through a calcium mediated mechanism, thus opening up possibilities for studies of signal transductions through activation of the GABAA receptor present on the sperm surface.
Sheng li xue bao : [Acta physiologica Sinica]  •  1998  |  View Paper
Several neurotransmitters (noradrenaline, GABA , 5 HT and dopamine) all inhibit Ca 2÷ currents recorded from chick sensory neurones, this shows convergence of receptor mechanisms onto a single effector, the Ca 2+ channel.
General pharmacology  •  1989  |  View Paper
In [35S]-GTPgammaS binding assays, Ca2+ ion (1 mM) enhanced the potency of the agonists GABA and 3-aminopropylphosphinic acid (3-APA) and that of the antagonist CGP55845, but not that of the GABA(B) receptor agonist (-)-baclofen.
Neurochemistry International  •  2005  |  View Paper
These findings suggest that dopamine-induced calcium signal may stimulate release of neuromodulators such as GABA and adrenaline and thus suppress spontaneous calcium oscillations in neurons.
Cell calcium  •  2021  |  View Paper
GABA repolarized the membrane and shut off such calcium rises.
Journal of pineal research  •  2016  |  View Paper
On activation, both GABAR types triggered synergistically intracellular calcium rise.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  •  2010  |  View Paper
We found that GABA induces membrane depolarization and Ca2+ elevation in NG2 cells, a process requiring activation of GABAA receptors, Na+ channels, and Na+/Ca2+ exchangers (NCXs), but not Ca2+ channels.
The Journal of cell biology  •  2009  |  View Paper
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