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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Aspartate

Research Papers that Mention the Interaction

During treatment, an increase in the extracellular amino acids alanine, glycine, glutamate, aspartate , serine, threonine, and taurine was found demonstrating a significant influence on the intracellular pool of free amino acids induced by DAB.
Journal of Neuro-Oncology  •  2006  |  View Paper
The ratio of excitatory amino acids aspartate and glutamate) to inhibitory amino acids (taurine and GABA ) was significantly higher in focal tissue compared to nonfocal.
Neurochemical Research  •  2004  |  View Paper
In the head-injured patients, the concentrations of aspartate , glutamate, and glycine were 2− to 8-fold higher, and the concentration of GABA 56− to 317-fold higher than control values; the concentration of serine was unaffected.
Neuroreport  •  1994  |  View Paper
The concentrations of aspartate , glutamate, and GABA had mutually significant positive correlations (p<0.05), but had significant negative correlations with the concentrations of some neutral amino acids.
Journal of neural transmission. Parkinson's disease and dementia section  •  1993  |  View Paper
Aspartate and glycine concentrations were significantly lower in many and GABA and taurine concentrations in some cochlear nucleus and superior olive regions.
Hearing Research  •  2017  |  View Paper
The α4β2 selective agonist 5IA85380 was significantly less potent in inducing GLU overflow while the overflow of ASP and GABA were almost inconsistent.
European journal of pharmacology  •  2014  |  View Paper
We found that the currents induced by aspartate at 100 μmol L−1 were suppressed by the pre-perfusion of GABA at 100 μmol L−1, indicating cross-inhibition of NMDA receptors by activation of GABAA receptors.
Science China Life Sciences  •  2011  |  View Paper
significantly restored the heat stress induced decline in GABA and glycine and thwarted the elevation of glutamate and aspartate in various brain areas.
Journal of Neural Transmission  •  2005  |  View Paper
Although aspartate reduced GABA immunoreactivity, specifically in amacrine cells of E18 retinas, it was not efficient to promote GABA release from retinas at E14.
In the retina, it has been shown that glutamate and aspartate and their agonists kainate and NMDA promote the release of GABA.
Neurochemical Research  •  2004  |  View Paper
Here we show that L-aspartate promotes the release of GABA acting selectively on the NMDA receptor subtype.
Neurochemistry International  •  1998  |  View Paper
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