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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Aripiprazole

Research Papers that Mention the Interaction

Aripiprazole enhances gamma-aminobutyric acid (GABA) transmission in certain brain areas, and it is widely agreed that low GABA activity may contribute to catatonic symptoms.
Fortschritte der Neurologie-Psychiatrie  •  2020  |  View Paper
Local administration of aripiprazole in mPFC increased dopamine and decreased GABA releases, whereas local administration of sulpiride had no effect on dopamine or GABA.
Neuropharmacology  •  2012  |  View Paper
Conclusion Our results suggest that aripiprazole administration results in increased GABA transmission in the prefrontal regions, and that these increases may be a neural basis of aripiprazole's clinical benefits on an improvement of social competence.
Psychiatry investigation  •  2013  |  View Paper