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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Anticholinergic Agents

Research Papers that Mention the Interaction

In the ltBG, the GABA concentration was positively correlated with the dose of the anticholinergics (rs=0.403, p=0.015).
Schizophrenia Research  •  2010  |  View Paper
This in vivo study demonstrates that anticholinergic drugs perfused at the level of the substantia nigra can modulate dopamine and GABA levels and attenuate the L-dopa decarboxylation in the striatum, possibly via modulation of the nigrostriatal dopaminergic system.
European journal of pharmacology  •  2000  |  View Paper
The present study examines the possibility that the effects of GABA on antral peptide release may be mediated, in part, through stimulation of antral cholinergic neurons.
Gastroenterology  •  1986  |  View Paper
It was found that atropine reversed antinociception induced by THIP but not that induced by baclofen in the 48 degrees C test, whereas the anticholinergic drug blocked the response to both GABA agonists when the stimulus was provided by a 55 degrees C hot-plate.
Neuropharmacology  •  1985  |  View Paper