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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Anesthetics, General
Research Papers that Mention the Interaction
“ General anesthetics are known to act in part by binding to and altering the function of pentameric ligand-gated ion channels such as nicotinic acetylcholine and γ-aminobutyric acid type A receptors.”
Combining Mutations and Electrophysiology to Map Anesthetic Sites on Ligand-Gated Ion Channels.“In vivo, however, the functional relevance of enhancing GABAergic neurotransmission in mediating essential components of the general anesthetic state is unknown.”
Increased &ggr;-Aminobutyric Acid Levels in Mouse Brain Induce Loss of Righting Reflex, but Not Immobility, in Response to Noxious Stimulation“ General anesthetics allosterically modulate the activity of neuronal γ-aminobutyric acid , type A (GABAA), receptors.”
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