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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Gamma-Aminobutyric Acid and 1-Octanol

Research Papers that Mention the Interaction

Coapplications of n-octanol increased peak currents evoked by 3 microM GABA with an EC50 of 190 microM and an nH of 1.8.
Molecular pharmacology  •  1999  |  View Paper
Ethanol (30-300 mM), n-butanol (1-30 mM), n-hexanol (30-1000 microM) and n-octanol (3-100 microM) enhanced the initial peak current evoked by 30 microM GABA in a dose-dependent manner.
Ethanol (300 mM) and n-octanol (30 and 100 microM) shortened the decay time course of the current induced by 30 microM GABA to 66, 74 and 52% of control, respectively.
The Journal of pharmacology and experimental therapeutics  •  1991  |  View Paper