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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
1-Octanol
Research Papers that Mention the Interaction
“Coapplications of n-octanol increased peak currents evoked by 3 microM GABA with an EC50 of 190 microM and an nH of 1.8.”
Agonist and potentiation actions of n-octanol on gamma-aminobutyric acid type A receptors.“Ethanol (30-300 mM), n-butanol (1-30 mM), n-hexanol (30-1000 microM) and n-octanol (3-100 microM) enhanced the initial peak current evoked by 30 microM GABA in a dose-dependent manner.”
“Ethanol (300 mM) and n-octanol (30 and 100 microM) shortened the decay time course of the current induced by 30 microM GABA to 66, 74 and 52% of control, respectively.”
Modulation of gamma-aminobutyric acid receptor-channel complex by alcohols.
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