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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
1,3-Dpcpx
Research Papers that Mention the Interaction
“After reinstatement, application of the A1 adenosine antagonist 1,3-dipropyl-8-cyclopentylxanthine increased GABA tone to inhibit the CRF-R2 action.”
CRF-R2 and the Heterosynaptic Regulation of VTA Glutamate during Reinstatement of Cocaine Seeking“ DPCPX (0.3, 0.15 microgram, icv) significantly decrease GABA and increase Glu/GABA in brain of mice.”
“Coupling efficacy of micro-receptors to presynaptic inhibition of GABA release was increased in dependent mice in the presence of DPCPX.”
“ DPCPX per se enhanced GABA release, indicating inhibition of the release by endogenous adenosine.”
“The selective A1 antagonist DPCPX (10–100 nM) increased GABA release, suggesting that endogenous adenosine tonically inhibits GABA release.”
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