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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Galantamine
supplement:
Melatonin
Research Papers that Mention the Interaction
“Cell incubation with increasing concentrations of galantamine (10–300 nm) or melatonin (0.3–10 nm) for 24 hr, followed by a 24‐hr period with R/O, caused a concentration‐dependent protection; maximum protection was achieved with 300 nm galantamine (56% protection) and 10 nm melatonin (50% protection).”
“Combination of subeffective concentrations of melatonin (0.3 nm) and galantamine (30 nm) caused a synergistic and significant protection that was similar to the maximum protection afforded by effective concentrations of melatonin or galantamine alone.”
“This investigation evaluated a possible synergistic neuroprotective effect of subeffective concentrations of combined galantamine and melatonin.”
Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH‐SY5Y neuroblastoma cells“Most effective was the finding that combination of sub-effective concentrations of melatonin (1 nM) and galantamine (10 nM) provided a synergic anti-apoptotic effect and reduction of most of the AD-related pathological hallmarks observed in the βA/OA model.”
Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
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