Possible Interaction: Galactose and Oligosaccharides

“In addition D-galactosamine interfered with oligosaccharide processing , leading to the formation of some carbohydrate side chains remaining in an endoglucosaminidase H sensitive, i.e., not completely processed, form.”

“The inhibitory effect of D-galactosamine on de novo glycosylation as well as on oligosaccharide processing lasted for at least 24 h after it had been removed from the cells.”

“Each of the carbohydrate constituents, the peracetylated glucitol, the galactose , the glucosamine, and the fucose contribute specific mass increments to the molecular weight of the oligosaccharide.”

“The galactose was trimmed from rhodopsin's oligosaccharide presumably after its role was complete.”

“RT-qPCR results showed that AOS suppressed the down-regulation of Nrf2 and HO-1 mRNA expressions induced by D-gal.”

“Western blot results showed that AOS attenuated the damage of D-gal in the protein expressions of antioxidative enzymes SOD1, SOD2 and CAT.”

“Moreover, the synthetic rate of galacto-oligosaccharides was enhanced by 1.1-fold and 1.9-fold with the addition of 0.7 M galactose or glucose, respectively.”

“We demonstrate that the activity of two distantly related O antigen ligases is dependent on the presence of N-acetylglucosamine, and substitution of an additional sugar, i.e. galactose , alters the site specificity of the core oligosaccharide necessitating discriminative WaaL types.”

“The presence of galactose and glucose at the concentrations encountered near maximum GOS greatly inhibited the reactions and reduced GOS yield by as much as 15%.”

“Substitution of the terminal N-acetylglucosamine residues of oligosaccharides by galactose completely abolishes their affinity to the column.”