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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Galactose and Nitric Oxide



Research Papers that Mention the Interaction

We observed that, like on glucose, S. aureus withstands high concentrations of NO when using galactose.
Front. Microbiol.  •  2017  |  View Paper
However, D-GalN slightly enhanced NO production during 24 to 48 hours.
Our results showed that the spontaneous and LPS-induced NO production was completely blocked by D-GalN during 0 to 24 hours.
Toxicology mechanisms and methods  •  2008  |  View Paper
However, the production of nitric oxide and superoxide and the expression and activity of SOD2 were significantly reduced after 5 days in galactose culture.
Arthritis Research & Therapy  •  2015  |  View Paper
D-GalN augmented the NO production in RAW 264.7 cells stimulated with either TNF-alpha and interferon-gamma.
D-GalN augmented the production of NO , but not tumor necrosis factor (TNF)-alpha in LPS-stimulated RAW 264.7 cells.
It was therefore suggested that D-GalN might augment LPS-induced NO production through the generation of intracellular ROS.
Pretreatment of D-GalN augmented the NO production whereas its post-treatment did not.
FEMS immunology and medical microbiology  •  2004  |  View Paper
Similarly, administration of an NO donor to rats treated with TNFalpha and D-galactosamine also prevented the increase in caspase-3-like activity as measured in liver homogenates.
The Journal of biological chemistry  •  1997  |  View Paper