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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Gadolinium
supplement:
Iodine
Research Papers that Mention the Interaction
“Adding a small amount of iodinated contrast to gadolinium results in a significant improvement in the radiographic density and DSA image quality of gadolinium.”
“When using iodinated and gadolinium contrast agents , there are potential complications including allergic reactions, lactic acidosis, and nephrogenic systemic fibrosis.”
“Froeling et al. [3] found statistically significant correlation between contrast agent kinetics curves for spectral contrast-enhanced breast tomosynthesis using iodine and MRI with gadolinium.”
“For patients who received iodinated contrast in combination with Gd , there was a trend toward a higher risk for developing ARF as compared with those receiving only Gd.”
“Although iodinated contrast seems safe to use in pregnancy, intravenous gadolinium is contraindicated and should be used only when absolutely essential.”
Guidelines for Computed Tomography and Magnetic Resonance Imaging Use During Pregnancy and Lactation“In fact, 1.8 to 4.8 g of iodine , equally attenuated with a relatively high dose (0.2 to 0.4 mmol) of a gadolinium chelate , is a low iodine dose and could hardly have any important nephrotoxic effects.”
“We experienced DSA examination using a gadolinium contrast agent in a patient contraindicated for iodine.”
“Recent experiments using CT and transmission radiography show that Gd agents can increase image contrast by up to a factor of 2 relative to more commonly used iodinated agents on an equi-molar basis.”
“ Gadolinium outperforms iodine for spectra above (and vice versa below) about 72 kVp, depending slightly on spectrum filtration, object thickness, and detector type.”
“Similarly, beam-hardening artifacts in performing video densitometry with iodine would be reduced with gadolinium.”
“When administered to very small organs, the use of gadolinium reduces the concentration required for visibility by at least a factor of 3 over that required when using iodine.”
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