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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Furosemide and Glycine

supplement:

Glycine

Research Papers that Mention the Interaction

Furosemide reduced hypoosmotically-evoked releases of taurine, glycine , alanine and phosphoethanolamine.
European journal of pharmacology  •  1998  |  View Paper
Furosemide at a concentration of 1 mM depressed the maximal peak amplitude of the dose-response curve for either GABA or glycine to about 70% of control.
Furosemide inhibited the peak amplitude of either GABA or glycine current in a dose-dependent manner; its half-maximal concentration for them was some 2 and 1 mM, respectively.
These results indicate that furosemide inhibits in a noncompetitive fashion GABA and glycine receptor-channels in septal neurons.
Brain Research  •  1997  |  View Paper
Furosemide (0.1-0.5 mM) changed equilibrium potentials of inhibitory postsynaptic currents, gamma-aminobutyric acid-A (GABAA) or glycine receptor-mediated Cl- currents by a blockade of Cl(-)-outward transport.
Journal of neurophysiology  •  1996  |  View Paper