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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Fucose
drug:
Trastuzumab
Research Papers that Mention the Interaction
“Here, we show that removing fucose from trastuzumab (Herceptin) increased its binding to FcgammaRIIIa, enhanced antibody-dependent cell-mediated cytotoxicity, and more than doubled the median progression-free survival when compared with conventional trastuzumab in treating preclinical models of HER2-amplified breast cancer.”
Superior in vivo efficacy of afucosylated trastuzumab in the treatment of HER2-amplified breast cancer.
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