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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Fucose
drug:
Mycophenolic Acid
Research Papers that Mention the Interaction
“Furthermore, MPA can also induce apoptosis of immune cells and is known to inhibit synthesis of fucose- and mannose-containing membrane glycoproteins altering the surface expression and binding ability of adhesion molecules.”
Effect of mycophenolic acid in experimental, nontransplant glomerular diseases: new mechanisms beyond immune cells“ MPA also depletes pools of GTP in human lymphocytes and monocytes, thereby inhibiting the synthesis of fucose- and mannose-containing saccharide components of membrane glycoproteins.”
“ MPA , an inhibitor of IMP dehydrogenase, depletes GTP and thereby suppresses transfer of mannose and fucose to proteins.”
“ MPA preferentially inhibits the type II isoform of inosine monophosphate dehydrogenase, depletes GTP, suppresses transfer of mannose and fucose to glycoproteins, and prevents lymphocyte proliferation in vivo.”
APOPTOSIS OF SUPERANTIGEN-ACTIVATED T CELLS INDUCED BY MYCOPHENOLATE MOFETIL TREATMENT1
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