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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Fosfomycin and Glutathione

supplement:

Glutathione

Research Papers that Mention the Interaction

FosA, FosB, and FosX confer resistance to fosfomycin by adding glutathione , l-cysteine, or a hydroxyl group, respectively, to the oxirane ring of this antibiotic, rendering it inactive (see references 2, 3, 4, and 10 and references therein).
FosA, FosB, and FosX confer resistance to fosfomycin by adding glutathione , l-cysteine, or a hydroxyl group, respectively, to the oxirane ring of this antibiotic, rendering it inactive (see references 2, 3, 4, and 10 and references therein).
Antimicrobial agents and chemotherapy  •  2005  |  View Paper
The reaction catalyzed by FosA involves the attack by glutathione on fosfomycin to yield the product 1-(S-glutathionyl)-2-hydroxypropylphosphonic acid.
Journal of the American Chemical Society  •  2002  |  View Paper