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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Formononetin
drug:
Bortezomib
Research Papers that Mention the Interaction
“In addition, FT augmented tumor growth-inhibitory potential of Bor in MM preclinical mouse model.”
“It was observed that FT enhanced the apoptosis caused by bortezomib (Bor) and mitigated proliferation in MM cells, and these events are regulated by nuclear factor-κB (NF-κB), phosphatidylinositol 3-kinase (PI3K)/AKT, and activator protein-1 (AP-1) activation.”
Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model“Co-treatment with other chemotherapy drugs such as bortezomib , LY2940002, U0126, sunitinib, epirubicin, doxorubicin, temozolomide, and metformin enhances the anticancer potential of both formononetin and the respective drugs through synergistic effect.”
Formononetin: A Review of Its Anticancer Potentials and Mechanisms
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