“ Folic acid treatment for 12 months increased the plasma level …% (95% confidence interval [CI], 72% to 170%), the vasodilatory response to acetylcholine by 124% (95% CI, 36% to 212%), and the ischemia-mediated hyperemic responses …% to 96%) and in the forearm vasculature by 47% (95% CI, 21% to 73%).”