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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Folic Acid
supplement:
Tyrosine
Research Papers that Mention the Interaction
“It was interesting that oral administration of folic acid , which itself has no biopterin effect, reduced serum phenylalanine and increased serum tyrosine and serum serotonin.”
A case of tetrahydrobiopterin deficiency due to a defective synthesis of dihydrobiopterin“Rienits (13) found that folic acid stimulated the metabolism of tyrosine with liver homogenates prepared from scorbutic guinea pigs.”
“Several observations in Go have suggested that folic acid may have a role in the oxidation of tyrosine , although no specific function of the vitamin in the metabolism of this ammo acid has been established.”
The effect of folic acid on tyrosine metabolism in guinea pigs.“The results of these studies indicated that folic acid associates with phenylalanine and tyrosine with binding constants ranging from 1.46 × 104 to 2.66 × 104 M−1.”
An analysis of the interactions between folic acid and aromatic guest molecules“ Folic acid , a competitive inhibitor, protected against modification of the tyrosines and the associated activity losses; however, the oxidation of the single sulfhydryl group and the initial 20 to 30% activity loss were unaffected.”
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