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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Folic Acid
drug:
Sulfanilamide
Research Papers that Mention the Interaction
“57, 151, 1944) reported that a decreased amount of folic acid was produced in cultures containing sulfanilamide by both sensitive and resistant strains of Escherichia coli, and Harrison and Clapper (Bacteriol.”
DIFFERENCES IN THE SYNTHESIS OF FOLIC ACID AND 5-AMINO-4-IMIDAZOLECARBOXAMIDE IN SULFATHIAZOLE SENSITIVE AND RESISTANT STRAINS OF ESCHERICHIA COLI“ Sulfanilamide growth inhibition was reversed competitively by PABA and by very high concentrations of folic acid.”
Action of sulfanilamide on Ochromonas malhamensis.“ Sulphanilamide inhibits the synthesis of folic acid activity by Lactobacillus arabinosus.”
Synthesis of a compound with folic acid activity by Lactobacillus arabinosus 17-5“Summary 1) Acetylation of sulfanilamide and of isoniazid in pigeon liver extracts was markedly inhibited (non-competitively) by 4-amino analogues of folic acid.”
“SEVAG, M. G., KoFT, B. W., and STEERS, E. Failurie of folic acid to antagonize sulfanilamide non-competitively in the growth of Lactobacillus arabintosus 17-5.”
“The data presented here show that sulfanilamide SA ) inhibits the growth of L. arabinosus in the presence of FA.”
“Later, Winkler and de Haan (1948) reported that, in the presence of methionine and adenine, serine and pteroylglutamic acid (or thymine) would reverse the inhibitory effects of higher concentrations of SAN.”
“Also, Miller (2) found the synthesis of folic acid by Escherichia coli to be inhibited by sulfanilamide.”
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