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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Folic Acid
drug:
Sulfadiazine
Research Papers that Mention the Interaction
“ Pteroylglutamic acid had no significant effect on the antimalarial activity of quinine, chloroquine or pamaquine, but completely inhibited the effect of sulfadiazine.”
Inhibition of the Antimalarial Activity of Chlorguanide by Pteroylglutamic Acid“After the discovery that the 6BC strain of the psittacosis virus was susceptible to sulfadiazine (Early and Morgan, 1946a,b), Morgan (… that PABA definitely antagonized the chemotherapeutic action of sulfadiazine on this virus in eggs and that the chemotherapeutic action of the sulfadiazine was also … acid and pteroylglutamic acid.”
THE REVERSAL BY PABA OF SULFONAMIDE INHIBITION OF THE VIRUSES OF LYMPHOGRANULOMA VENEREUM AND MOUSE PNEUMONITIS“ Sulfadiazine is a bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria.”
Physicochemical Stability of an Oral Suspension of Trimethoprim 20 mg/mL in Combination with Sulfadiazine 200 mg/mL in PCCA Base SuspendIt.“F lic acid i ncompletely antagonized the effect of su lfadiazine, but did not antagonize the effect of pyrimethamine.”
“Summary The chemotherapeutic action of sulfadiazine on psittacosis virus (strain 6BC) is antagonized competitively by p-aminobenzoic aoid and noncompetitively by pteroylglutamic acid.”
“The effects of certain analogues of pteroylglutamic acid and of pteroic acid on the growth of psittacosis virus and its inhibition by sulfadiazine are reported.”
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