supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Folic Acid
supplement:
Serine
Research Papers that Mention the Interaction
“In the nucleus, FA up-regulated KIS, which in turn increased p27 phosphorylation at serine 10 (Ser10), subsequently resulting in cytosolic translocation of p27 and forming the p27-RhoA complex, thereby causing RhoA degradation, and eventually inhibited COLO-205 cell migration.”
Folic acid inhibits colorectal cancer cell migration.“Daily 5-mg doses of folic acid supplementation for 4 weeks significantly reduced plasma concentrations of total homocysteine (p < 0.01) and serine (p < 0.001).”
“A possible relation between …-carbon atom of serine … folic acid is suggested by the finding that the Streptococcus lactis R factor (rhizopterin) has the structure of iV”-formylpteroic acid (lo), … factor and the N’O-formyl derivative of folic acid show folic acid activity for certain organisms (11, 12).”
“The activity was further depressed when glycine or serine was added to the diet deficient in folic acid.”
Effect of dietary folic acid deficiency on serine-glycine interconversion and the activity of liver serine hydroxymethyl transferase in the chick.“The results show that Ser residue may be essential for substrate-binding or catalysis of PGA.”
[Effect of mutagenesis at Ser 177 residue in penicillin G acylase on activity of the enzyme].
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback