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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Folic Acid
supplement:
Riboflavin
Research Papers that Mention the Interaction
“With respect to micronutrients, the ingestion of vitamin B2 significantly increased, as well as folic acid and calcium (p < 0.001) in ANP, and magnesium and calcium (p < 0.001) in ANR.”
[Evaluation of the utility of a Nutrition Education Program with Eating Disorders].“ Riboflavin supplementation may have blunted the effect of folic acid , which resulted in a diminished reduction of tHcy in our subjects.”
“High riboflavin concentration (500 nmol/L) increased NBUD levels by 25% (compared with 0 nmol/L riboflavin) in folate-deficient conditions (20 nmol/L folic acid medium; P<0.05), and there was an interaction between folic acid and riboflavin that affected NBUD levels (P=0.042).”
“Of a number of compounds classified as antioxidants and known to have some stabilizing effect in other pharmaceutical preparations, it was found … acid, butylated hydroxyanisole, and ethyl hydrocaffeate substantially improved the stability of folic acid in certain types of acqueous and simple solutions containing folic acid in … of riboflavin.”
“ Folic acid undergoes oxidative cleavage on exposure to light, and riboflavin markedly intensifies this action of light.”
“Supplementation of folic acid alone gave lower values than both vitamins, however administration of only a fifth of the full dosage of riboflavin to rats receiving folic acid improved the haemoglobin values significantly.”
Effect of riboflavin and folic acid supplementation on some haematopoietic parameters in the rat.“Supplementation of these diets with riboflavin brought about no effect on the growth; the combination of riboflavin and PGA overcame the growth depression to a considerable extent and also brought about a marked increase in gain per unit of food consumed.”
“The data would suggest that there is an interrelationship between riboflavin and PGA in white cell production.”
“The main component of the media responsible for the generation of ROS was riboflavin, but tryptophan, tyrosine, pyridoxine, and folic acid enhanced the effect of riboflavin.”
Light-dependent generation of reactive oxygen species in cell culture media.“The second-order rate constants for the bimolecular interaction of folic acid and riboflavin have been determined in the pH range 4.0-9.0.”
“The present experiments show that isoriboflavin markedly stimulates acid production by Lactobacillus easei in the presence of suboptimal levels of riboflavin or FAD.”
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