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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Folic Acid and Probenecid

supplement:

Folic Acid

Research Papers that Mention the Interaction

Consequently, CEM-7A cells displayed a 5-fold decrease in the [3H]folic acid efflux rate constant, which was identical to that obtained with parental CEM cells, when their folic acid efflux was blocked (78%) with probenecid.
The Journal of Biological Chemistry  •  2003  |  View Paper
Membrane transport inhibitors SITS, DIDS, probenecid and endocytic inhibitor, colchicine significantly inhibited the [3H]folic acid uptake indicating the involvement of receptor/transporter mediated process.
Current eye research  •  2011  |  View Paper
Probenecid decreased the level of uptake of radiolabeled folic acid , suggesting a transport-based mechanism linked to folate salvage.
Antimicrobial Agents and Chemotherapy  •  2003  |  View Paper