Possible Interaction: Folic Acid and Multivitamin Preparation

“Use of multivitamins reduced the risk (odds ratio [OR], 0.5; 95% confidence interval [CI], 0.2-1.0) as opposed to use of folic acid supplements only (OR, 1.3; 95% CI, 1.0-1.8).”

“However, tHcy was not normalized in the majority of patients receiving preparation A. CONCLUSION The reduction of tHcy achieved by a multivitamin containing 800 microg folic acid was substantial and even higher than the reduction reported in supplementation studies using higher doses of folic acid alone.”

“ Vitamin supplements produced significant improvement in pre-existing deficiencies of riboflavin, pyridoxine and folic acid.”

“Food fortification with folic acid and increased use of vitamin supplements have raised concerns about high folic acid intake.”

“In recent years, there has been a great deal of epidemiologic evidence demonstrating that women who received multivitamins containing folic acid periconceptionally had significantly reduced occurrence and recurrence risks for producing infants with such malformations.”

“ Multivitamin use (sporadic and consistent) also increased the proportion of individuals who exceeded the tolerable upper intake level for folic acid to 8%–10%.”

“However, evidence showed that women receiving multivitamins plus iron and folic acid had reduced risk for stillbirth.”

“Multivitamin supplementation There was evidence of a decrease in the risk for stillbirth among women receiving multivitamins plus iron and folic acid compared iron and folate only groups (RR 0.92, 95% CI 0.85 to 0.99, 10 trials, 79,851 women; high-quality evidence).”

“The key issue of my … the fact that taken a folic acid before getting pregnant and … supplementary diet with multivitamin supplements for pregnants increases the chance of a higher body mass of a neonate and … is supplementary faster in a pregnancy the body mass of a neonate is higher.”

“BACKGROUND Evidence exists for an association between use of vitamin supplements with folic acid in early pregnancy and reduced risk for offspring with conotruncal heart defects.”

“The key issue of my … the fact that taken a folic acid before getting pregnant and … supplementary diet with multivitamin supplements for pregnants increases the chance of a higher body mass of a neonate and … is supplementary faster in a pregnancy the body mass of a neonate is higher.”