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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Folic Acid
drug:
Metformin
Research Papers that Mention the Interaction
“CONCLUSION These findings suggest that B-group vitamins and fo ic acid ad ministration counteract the Hcy-increasing effect seen with met formin th erapy.”
Administration of B-group vitamins reduces circulating homocysteine in polycystic ovarian syndrome patients treated with metformin: a randomized trial.“The absorption of folic acid and vitamin B12 is importantly decreased by the prolongued use of metformin , which is the first choice drug in uncomplicated diabetes, thus these two nutrients have been found deficient in the disease and most probably need to be supplemented regularly.”
“After folic acid and metformin administration, mean of Hcy, HOMA-IR, TNF-α, and IL-8 decreased significantly (P < 0.05).”
Effect of folic acid and metformin on insulin resistance and inflammatory factors of obese children and adolescents
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