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“Since long-lasting effects may be mediated by DNA methylation, we hypothesized that providing supplemental folic acid FA ), a methyl donor, during early life, would enhance the positive effect of ISO to bone health.”
The Journal of nutritional biochemistry • 2015 | View Paper
“CONCLUSION Folic acid should be the main protective factor of NTDs, and is flavone mi ght reinforce the protective effects of fol ic th e acid on NTDs by increasing the antioxidative ability, however, the effect is related with the ratio of the two factors.”
“RESULTS The interaction of fo ic acid an d iso flavone ha d significant effect on the indices related with antioxidation (P < 0.05).”