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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Folic Acid and Glutathione

supplement:

Folic Acid

supplement:

Glutathione

Research Papers that Mention the Interaction

In summary, oral folic acid supplementation in T2DM reduced plasma Hcy and increased glutathione levels.
Diabetes, nutrition & metabolism  •  2004  |  View Paper
FA supplementation changed the malondialdehyde and glutathione levels and superoxide dismutase (SOD) and glutathione peroxidase activities in the hippocampus.
The Journal of nutritional biochemistry  •  2019  |  View Paper
Moreover, cerebellar MS, CBS enzyme activity, GSH , and GSH/GSH ratio increased following folic acid treatment.
Neurotoxicity Research  •  2019  |  View Paper
Results: GSH increased significantly in cortex of rats treated with FA.
Archives of physiology and biochemistry  •  2018  |  View Paper
Moreover, folic acid significantly decreased levels of lipid peroxidation, protein nitrotyrosination and glutathione depletion in diabetic wounds.
Journal of nutritional science and vitaminology  •  2018  |  View Paper
Finally, GSH increased to control levels with folic acid supplementation.
It has also been demonstrated that folic acid increases GSH levels, improving the antioxidant status and revealing a hepatoprotective effect during binge drinking.
Alcohol and alcoholism  •  2016  |  View Paper
Additional experiment showed that folic acid attenuated LPS-induced glutathione ( GSH ) depletion in maternal liver and placentas.
Toxicology letters  •  2014  |  View Paper
Folic acid-supplemented diets suppressed the AOM-induced ACF and GSH depletion in a dose-dependent manner and augmented the TAC.
Experimental biology and medicine  •  2011  |  View Paper
Folic acid slightly increased the ratio of reduced glutathione to oxidized glutathione in +db/+db mice.
The Journal of nutritional biochemistry  •  2010  |  View Paper
Preincubation of the PGA with glutathione or cysteine prevents the inactivation; i.e., the sulfhydryl binding region of the prostaglandin must be free for enzyme to be inactivated.
Lipids  •  2006  |  View Paper
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