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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Folate
drug:
Tetrahydrofolate
Research Papers that Mention the Interaction
“ Folate plays a critical role in regulating the amount of tetrahydrofolate in the cell that is utilized for DNA replication, and proliferation of the erythropoietic system.”
Bioinformatic analysis of dihydrofolate reductase predicted in the genome sequence of Lactobacillus pentosus KCA1.“It is indeed probable that the increased availability of the preferred substrate of pteroylpolyglutamate synthetase, i.e. tetrahydrofolate , enhances conversion of folate into coenzyme forms.”
Distribution of pteroylglutamates in rat liver during regeneration after partial hepatectomy.“Dihydrofolate, tetrahydrofolate , 5-formyl tetrahydrofolate, 5-methyl tetrahydrofolate, aminopterin, and amethopterin are inhibitors of folate influx.”
Transport of folate compounds into Lactobacillus Casei.“When the concentrations of folate present in the growth medium exceed 1.4 x 10-9 m, the specific activity of 10-formyl tetrahydrofolate synthetase and dihydrofolate reductase is decreased, possibly through repression of the enzyme.”
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