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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Folate and Levomefolate

supplement:

Folate

supplement:

Levomefolate

Research Papers that Mention the Interaction

Addition of 0–6 μM-5-methyltetrahydrofolate produced a dose-dependent increase in the lag time, suggesting that folate may have a direct anti-oxidant role in vivo, which is independent of any indirect effects through lowering of homocysteine levels.
British Journal of Nutrition  •  2001  |  View Paper
Folate supplementation with or without serine significantly increased or tended to increase hepatic 5-methyltetrahydrofolate concentration together with methionine synthase (MS) and cystathionine β-synthase (CBS) activities and MS mRNA level in both rats fed 10C and rats fed 25S.
Journal of nutritional science and vitaminology  •  2012  |  View Paper
These findings suggest that l-methylfolate is bioactive and behaves predictably by increasing plasma levels of folate and decreasing homocysteine.
Reviews in obstetrics & gynecology  •  2011  |  View Paper