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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Fluphenazine
supplement:
Gamma-Aminobutyric Acid
Research Papers that Mention the Interaction
“These data suggest that fluphenazine treatment increased GABA transmission in specific subregions of the caudate and accumbens nuclei.”
Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain“Chronic desmethylimipramine treatment as well as iontophoresis of the blocking agents sotalol and fluphenazine which have been shown previously to block or reduce NE-mediated enhancement of GABA actions were ineffective in altering the facilitating effect of flurazepam on GABA.”
“The centrally acting drugs belonging to different groups- fluphenazine , trifluperidol, phthoracyzine, imipramine, diazepam, apomorphine, fentanyl, diphneylhydantoin, nonachlazine displayed in vitro an inhibitory effect on the uptake of gamma-aminobutyric acid by rat brain synaptosomes.”
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