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Last Updated: 2 years ago

Possible Interaction: Fluorouracil and Isothiocyanate

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drug:

Fluorouracil

supplement:

Isothiocyanate

Research Papers that Mention the Interaction

“The study revealed that additive or synergistic interactions were observed between 5-fluorouracil and both isothiocyanates , which enhanced the anticancer activity of 5-fluorouracil, particularly in colon cancer cell lines.”

In Vitro Evaluation of Sulforaphane and a Natural Analog as Potent Inducers of 5-Fluorouracil Anticancer Activity

Molecules • 2018 | View Paper

“The highest antagonistic effect in normal cells was obtained for co-administrated 5-fluorouracil and 2-oxoheptyl isothiocyanate at the fraction affected at 0.5 and 0.75.”

Combination treatment with 5-fluorouracil and isothiocyanates shows an antagonistic effect in Chinese hamster fibroblast cells line-V79.

Acta poloniae pharmaceutica • 2011 | View Paper

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