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Try: Ginkgo, Methotrexate, Glucosamine

Last Updated: 2 years ago

Possible Interaction: Fluorouracil and Iron, Dietary

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drug:

Fluorouracil

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

“ 5-FU also downregulates ferrochelatase, therefore, inhibits the incorporation of Fe into PpIX ring and induces massive accumulation of PpIX.”

The p53/MDM2/MDMX-targeted therapies—a clinical synopsis

Cell Death & Disease • 2020 | View Paper

“Distinct molecular mechanisms were identified for fenugreek: FE inhibited the expression of TYMS1 and TK1, synergizing with the chemotherapeutic drug 5-fluorouracil ( 5-FU ); meanwhile, HFE inhibited lipid metabolism targets, leading to diminished intracellular lipid content.”

Saponin-Rich Extracts and Their Acid Hydrolysates Differentially Target Colorectal Cancer Metabolism in the Frame of Precision Nutrition

Cancers • 2020 | View Paper

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