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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Fluorouracil and Glucose

supplement:

Glucose

Research Papers that Mention the Interaction

Notably, the inhibition rates of 5-fluorouracil on cells decreased over 48 h when treated with 4,500 and 9,000 mg/l glucose compared with 1,000 mg/l.
Molecular medicine reports  •  2015  |  View Paper
In the 1960s, researchers showed, in a series of in vitro experiments, that glucose increased the cytotoxicity of 5-fluorouracil.
American journal of clinical oncology  •  1998  |  View Paper
Insulin releasing test indicated that the early phase insulin response to glucose load was significantly diminished in animals treated with 5-FU at day 2.
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery  •  2010  |  View Paper
Results indicated that 5-FU uptake by the tumor slices was not dependent upon pHi, but was enhanced by the presence of glucose.
Cancer treatment reports  •  1976  |  View Paper
A significant potentiation of the antitumor action of 5-fluorouracil in rats bearing the Flexner-Jobling carcinoma is produced by the intraperitoneal administration of large doses of glucose.
Science  •  1963  |  View Paper