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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Fluorouracil and Elaidic Acid

supplement:

Elaidic Acid

Research Papers that Mention the Interaction

5-FU inhibited the growth of CT26 tumors, but co-treatment with either LA or EA abrogated this effect.
Aldehyde dehydrogenase activity in the cancer stem cells (CSCs), in response to concurrent treatment with 5-FU and either LA or EA , was increased compared with 5-FU treatment alone.
In addition, increased inhibition of growth was observed following concurrent treatment with EA and 5-FU.
Sequential treatment of LA followed by 5-FU abrogated the anticancer effects of 5-FU, and treatment with EA followed by 5-FU increased cancer cell growth in addition to abrogating the anticancer effects of 5-FU.
Oncology letters  •  2017  |  View Paper