Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 months ago

Possible Interaction: Fluorouracil and Alpha-lipoic acid

Research Papers that Mention the Interaction

Collectively, these findings demonstrate that LA induces CRC cell death independent of their p53 status and potentiates the cytotoxicity of 5-FU without causing DNA damage on its own, which makes it a candidate for tumor therapy.
Archives of Toxicology  •  2014  |  View Paper
α-LA treatment significantly increased tumor cell response to various apoptotic stresses, such as etoposide, 5-fluorouracil , UVC, γ-irradiation, hypoxia, and tumor necrosis factor α (TNFα).
Anti-cancer drugs  •  2013  |  View Paper