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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Fluorouracil and Alpha-lipoic acid

Research Papers that Mention the Interaction

Collectively, these findings demonstrate that LA induces CRC cell death independent of their p53 status and potentiates the cytotoxicity of 5-FU without causing DNA damage on its own, which makes it a candidate for tumor therapy.
Archives of Toxicology  •  2014  |  View Paper
α-LA treatment significantly increased tumor cell response to various apoptotic stresses, such as etoposide, 5-fluorouracil , UVC, γ-irradiation, hypoxia, and tumor necrosis factor α (TNFα).
Anti-cancer drugs  •  2013  |  View Paper