Possible Interaction: Fluorides and Xylitol

“However, Xylitol exerts an added benefit over fluoride alone in preventing caries increment.”

“Most new therapies try to enhance the effect of fluoride by adding other potentially active ingredients to the formulation, such as calcium, phosphate, stannous, xylitol , and arginine.”

“ External fluoride access may have confounded the measured anticariogenic effect of xylitol.”

“The addition of xylitol to existing fluoride regimes may be beneficial in the prevention of caries.”

“ External fluoride exposure and stimulated saliva flow may have confounded the measured anticariogenic effect of xylitol.”

“Compared with UN, this difference was significant in all groups with ld, but not in any group with delta Z. We concluded that tolerable levels of xylitol alone may not show a significant caries inhibiting and remineralizing effect, but may act as a caries inhibitor additively with fluoride.”

“In the presence of fluoride and xylitol , the proportion of lactic acid in the total amount of acidic end products decreased, while the proportion of formic and acetic acids increased.”

“The combination of fluoride and xylitol inhibited acid production more effectively than fluoride or xylitol alone.”

“The purpose of this study was to evaluate the combined inhibitory effect of fluoride and xylitol on acid production by mutans streptococci, Streptococcus mutans NCTC10449 and Streptococcus sobrinus 6715, from glucose under strictly anaerobic conditions at fixed pH 5.5 and 7.0.”

“This study indicates that fluoride and xylitol together have synergistic inhibitory effects on the acid production of mutans streptococci and suggests that xylitol has the potential to enhance inhibitory effects of low concentrations of fluoride.”

“This suggests that xylitol can augment the metabolic effects on S. mutans of low levels of fluoride.”

“ Xylitol affected the response to glucose but its effect was most marked in the presence of fluoride.”