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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Interestingly, antioxidants vitamin E and glutathione) can attenuate the inhibition of the receptor induced by fluoride.”
Oxidative stress might be a mechanism connected with the decreased alpha 7 nicotinic receptor influenced by high-concentration of fluoride in SH-SY5Y neuroblastoma cells.“Further, fluoride caused the enhanced Jun N-terminal kinase (JNK, c-Jun) and extracellular signal-regulated protein kinase (ERK) phosphorylation, which was reduced by VE or lycopene.”
Vitamin E and lycopene reduce coal burning fluorosis-induced spermatogenic cell apoptosis via oxidative stress-mediated JNK and ERK signaling pathways“In contrast, a decrease in the generation of ROS, an increase in SOD activity and the prevention of TBARS formation process were observed in spermatozoa of rats exposed to fluoride plus α‐tocopherol.”
“ Vitamin E reduced brain fluoride level and tissue oxidative stress but had no effect on arsenic.”
“Co-administration of calcium and Vitamin-E with fluoride resulted in a significant recovery from testicular disorders and oxidative stress in the testis and male accessory sex organs.”
“ DL-α-tocopherol , methylprednisolone, D-penicillamine significantly decreased the value of fluorescent products formed by iron-saccharate, whereas desferrioxamine was not effective.”
“ α-tocopherol and GSH both could reduce the amounts of fluorescent products and DNA strand breaks.”
Direct determination of diene conjugation and deoxyribonucleic acid (DNA) oxidative damage can explain the role of DTPA-Fe(2+)-O2 complex in a linoleic acid-DNA system.
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